According to the Bleacher Report, here are five NFL teams that are guaranteed to lose in Week 6.

The Cleveland Browns seem to have it rollling even after trading Trent Richardson to the Colts, but experts say they have a true test this week with Megatron and the Detroit Lions. Calvin Johnson is back with Mathew Stafford and Reggie Bush, so it looks like the Lions are too much for the Browns young defense.

The Michael Vickless Philadeplhpia Eagles play the Tampa Bay Buccaneers who are post Josh Freeman and ready to roll. With EJ Emanuel out, the Buffalo Bills will lose this week to the Cincinnati Bengals, who just defeated the New England Patriots. Jacksonville Jaguars will remain winless against the unbeaten Denver Broncos and Peyton Manning may set even more passing records. Not to mention, the Broncos are an incredible 28-point favorites in this one.

Last but not least, the Arizona Cardinals will hit a wall against the San Francisco 49ers, who just blew out the Houston Texans 31-3 this past Sunday on national TV.